SEGREGATION ANALYSES AND GENE-CENTROMERE DISTANCES IN ZEBRAFISH
Author(s) -
George Streisinger,
Fred D. Singer,
Charline Walker,
Donna Knauber,
Nancy A. Dower
Publication year - 1986
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/112.2.311
Subject(s) - biology , zebrafish , centromere , genetics , meiosis , gene , chiasma , cell division , mitosis , chromosome , cell
The gol-1, gol-2, alb-1 and spa-1 mutations affect pigment pattern in the zebrafish. We show here that these loci are unlinked to each other. In addition, gene-centromere distances were determined for these loci by analysis of half-tetrads obtained by the inhibition of the second meiotic division. The fractions of tetratype (second-division segregation) tetrads range from 0.24 (spa-1) to 0.89 (gol-1). The observation of greater than 0.67 second-division segregation indicates that the zebrafish has high chiasma interference.
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