Open AccessGENETIC ANALYSIS OF THE HAIRY LOCUS IN DROSOPHILA MELANOGASTER
Author(s) -
Philip W. Ingham,
Sheena M. Pinchin,
K.R. Howard,
David IshHorowicz
Publication year - 1985
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/111.3.463
Subject(s) - locus (genetics) , biology , drosophila melanogaster , genetics , complementation , allele , phenotype , mutant , gene
Mutations of the hairy locus in Drosophila may affect both adult chaeta differentiation and embryonic segmentation. In an effort to understand this phenotypic complexity, we have analyzed 30 mutant alleles of the locus. We find that the alleles fall into four groups according to their complementation properties, suggesting a structurally complex locus in which two distinct functions share a common coding region.
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