SEMIDOMINANCE OF rad18-2 FOR SEVERAL PHENOTYPIC CHARACTERS IN SACCHAROMYCES CEREVISIAE | Zendy

Ver W. Mayer | Zendy; Carol J. Goin | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

SEMIDOMINANCE OF rad18-2 FOR SEVERAL PHENOTYPIC CHARACTERS IN SACCHAROMYCES CEREVISIAE

Author(s) -

Ver W. Mayer,

Carol J. Goin

Publication year - 1984

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/106.4.577

Subject(s) - mitotic crossover , biology , genetics , allele , saccharomyces cerevisiae , dominance (genetics) , phenotype , ploidy , dna , chromosomal crossover , recombination , strain (injury) , gene , microbiology and biotechnology , anatomy

Inbred diploid yeast strains heterozygous or homozygous for the rad18-2 allele and carrying markers for detection of mitotic recombination were constructed. The homozygous rad18-2/rad18-2 strain was highly sensitive to killing by UV light, showed greatly elevated frequencies of spontaneous and induced mitotic recombination and was more sensitive to trimethoprim than the wild-type diploid. The heterozygous strain RAD18/rad18-2 was intermediate in its response for these same phenotypic characters. These findings are discussed in the light of other studies in which incomplete dominance of genes involved in some aspect of DNA repair has been reported.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research