SENSITIVITY OF TRYPTOPHAN, TYROSINE AND PHENYLALANINE MUTANTS OF SACCHAROMYCES CEREVISIAE TO PHENETHYL ALCOHOL
Author(s) -
James H. Meade,
Thomas R. Manney
Publication year - 1983
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/104.2.235
Subject(s) - saccharomyces cerevisiae , phenylalanine , biology , tyrosine , alcohol , tryptophan , genetics , mutant , mutation , biochemistry , yeast , amino acid , gene
Phenethyl alcohol inhibits the growth of many microorganisms. It is believed that the growth inhibition is mediated by its effect on the cell membrane. Differences between sensitive and resistant strains are suggested to be due to alterations in membrane structure. We report that, in some strains, an unexpected relationship exists between auxotrophy for tryptophan, tyrosine and phenylalanine and sensitivity to phenethyl alcohol.
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