ELECTROPHORETIC VARIATION FOR X CHROMOSOME-LINKED HYPOXANTHINE PHOSPHORIBOSYL TRANSFERASE (HPRT) IN WILD-DERIVED MICE | Zendy

Verne M. Chapman | Zendy; Paul G. Kratzer | Zendy; B A Quarantillo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

ELECTROPHORETIC VARIATION FOR X CHROMOSOME-LINKED HYPOXANTHINE PHOSPHORIBOSYL TRANSFERASE (HPRT) IN WILD-DERIVED MICE

Author(s) -

Verne M. Chapman,

Paul G. Kratzer,

B A Quarantillo

Publication year - 1983

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/103.4.785

Subject(s) - biology , hypoxanthine guanine phosphoribosyltransferase , genetics , hypoxanthine phosphoribosyltransferase , backcrossing , microbiology and biotechnology , hypoxanthine , chromosome , gene , x chromosome , genetic linkage , house mouse , mutant , biochemistry , enzyme

An electrophoretic variation for hypoxanthine phosphoribosyltransferase, HPRT, has been identified in samples of Mus spretus, a field mouse from southern Europe and in M. m. castaneus, a house mouse from southeast Asia. These mice will interbreed with laboratory mice to produce viable, fertile F1 progeny. The variation for HPRT segregates as an X chromosome gene in F1 and backcross progeny. Linkage analysis involving the markers Pgk-1 and Ags indicated a gene order of centromere--Hprt--Pgk-1--Ags in crosses involving both stocks of wild mice.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research