CHI-STIMULATED RECOMBINATION BETWEEN PHAGE Λ AND THE PLASMID Λdv | Zendy

Franklin W. Stahl | Zendy; Mary M. Stahl | Zendy; Lisa Young | Zendy; Ichizo Kobayashi | Zendy

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CHI-STIMULATED RECOMBINATION BETWEEN PHAGE Λ AND THE PLASMID Λdv

Author(s) -

Franklin W. Stahl,

Mary M. Stahl,

Lisa Young,

Ichizo Kobayashi

Publication year - 1982

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/102.4.599

Subject(s) - recombination , genetics , biology , homologous recombination , plasmid , dna , genetic recombination , phenotype , microbiology and biotechnology , gene

Chi promotes Rec-mediated recombination between phage λ DNA and the homologous plasmid λdv. In the absence of Chi, some of the interactions splice λdv into λ, whereas others patch information from λdv into λ. When Chi is in the phage DNA, splices and patches are increased in frequency by the same factor. This result strengthens the analogy between Chi and recombination-promoting elements in fungi. It also rules out one model for the previously reported orientation dependence of Chi phenotype.

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