MUTANTS OF PARAMECIUM DEFECTIVE IN CHEMOKINESIS TO FOLATE | Zendy

Mary C DiNallo | Zendy; Mark E. Wohlford | Zendy; Judith Van Houten | Zendy

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MUTANTS OF PARAMECIUM DEFECTIVE IN CHEMOKINESIS TO FOLATE

Author(s) -

Mary C DiNallo,

Mark E. Wohlford,

Judith Van Houten

Publication year - 1982

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/102.2.149

Subject(s) - complementation , mutant , biology , paramecium , genetics , mendelian inheritance , phenotype , allele , gene , mutation , mutagenesis , microbiology and biotechnology

Ten mutant lines of Paramecium tetraurelia defective in attraction to folate were isolated and examined. All mutants were normal in response to other attractants and repellents tested. One mutant was able to accumulate in folate given sufficient time. All mutations were recessive and behaved as single site Mendelian lesions. Complementation tests indicate that the mutants fall into three complementation groups. Mutants of Group 2 fall into two phenotypic classes and probably represent two alleles of the mutated fol2 gene. Possible sites of the mutants' blocks in chemoresponse are discussed.

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