UNEXPECTED BEHAVIOR IN TWO LOCUS GENETIC SYSTEMS: AN ANALYSIS OF MARGINAL UNDERDOMINANCE AT A STABLE EQUILIBRIUM | Zendy

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UNEXPECTED BEHAVIOR IN TWO LOCUS GENETIC SYSTEMS: AN ANALYSIS OF MARGINAL UNDERDOMINANCE AT A STABLE EQUILIBRIUM

Author(s) -

Alan Hastings

Publication year - 1982

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/102.1.129

Subject(s) - locus (genetics) , biology , generalization , phenomenon , allele , evolutionary biology , bifurcation theory , selection (genetic algorithm) , statistical physics , genetics , bifurcation , mathematical economics , mathematics , computer science , nonlinear system , physics , gene , mathematical analysis , quantum mechanics , artificial intelligence

The phenomenon of marginal underdominance at a stable equilibrium in a two-locus-two-allele deterministic selection model is studied analytically using bifurcation theory. This technique and additional numerical studies indicate several new aspects of the phenomenon that are of biological importance. Marginal underdominance can occur at both loci simultaneously and can be present in a model with small fitness differentials. This can occur for a fitness scheme that is a one parameter generalization of the classical symmetric fitness model.

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