Vedolizumab use in patients with inflammatory bowel diseases undergoing surgery: clinical trials and post-marketing experience | Zendy

Bo Shen | Zendy; Aimee Blake | Zendy; Karen Lasch | Zendy; Michael Smyth | Zendy; Fatima Bhayat | Zendy

Open Access

Vedolizumab use in patients with inflammatory bowel diseases undergoing surgery: clinical trials and post-marketing experience

Author(s) -

Bo Shen,

Aimee Blake,

Karen Lasch,

Michael Smyth,

Fatima Bhayat

Publication year - 2019

Publication title -

gastroenterology report

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.934

H-Index - 26

eISSN - 2052-0034

pISSN - 2304-1412

DOI - 10.1093/gastro/goz034

Subject(s) - medicine , vedolizumab , clinical trial , inflammatory bowel diseases , inflammatory bowel disease , surgery , general surgery , intensive care medicine , disease

Patients with inflammatory bowel diseases frequently require surgery, but immunotherapies used in disease management may increase the risk of post-operative complications. We investigated frequencies of post-operative complications in patients who received vedolizumab-a gut-selective antibody approved for the treatment of moderately to severely active ulcerative colitis and Crohn's disease-in clinical-trial and post-marketing settings.

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