Krukenberg tumour as the initial presentation of Peutz-Jeghers syndrome
Author(s) -
Bhavith Remalayam,
Santhosh Kuriakose,
P. V. Kambarath,
Ramachandran Thazhath Mavali
Publication year - 2013
Publication title -
gastroenterology report
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 26
eISSN - 2052-0034
pISSN - 2304-1412
DOI - 10.1093/gastro/got031
Subject(s) - peutz–jeghers syndrome , medicine , mucocutaneous zone , krukenberg tumor , stk11 , adenocarcinoma , presentation (obstetrics) , pathology , dermatology , metastasis , colorectal cancer , cancer , radiology , disease , kras
Peutz-Jeghers syndrome (PJS) is an hereditary syndrome characterized by gastrointestinal polyposis and mucocutaneous pigmentation. PJS patients are at increased risk of developing various cancers, especially of the gastrointestinal and gynaecological tracts. Colonic adenocarcinoma is one of the more common tumours that occur in PJS. We report a young lady presenting with a large ovarian tumour, later diagnosed to have PJS with colonic signet cell adenocarcinoma and synchronous ovarian metastasis.
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