BRAF mutation in multiple primary cancer with colorectal cancer and stomach cancer
Author(s) -
SeungHun Lee,
Byung-Kwon Ahn,
Seunghee Baek,
Hee Kyung Chang
Publication year - 2013
Publication title -
gastroenterology report
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 26
eISSN - 2052-0034
pISSN - 2304-1412
DOI - 10.1093/gastro/got004
Subject(s) - medicine , colorectal cancer , stomach cancer , cancer , primary cancer , mutation , oncology , cancer research , genetics , gene , biology
Recently, BRAF mutation testing has been introduced as a marker in differentiating Lynch syndrome from sporadic colorectal cancers or in predicting colorectal cancers with worse prognosis. Individuals with hereditary predisposition to cancer development are at an increased risk of developing multiple primary cancers. The purpose of this study is to identify mutation in the BRAF gene in multiple primary cancers with colorectal cancer and stomach cancer.
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