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How do base-pairing small RNAs evolve?
Author(s) -
Taylor B. Updegrove,
Svetlana A. Shabalina,
Gisela Storz
Publication year - 2015
Publication title -
fems microbiology reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.91
H-Index - 212
eISSN - 1574-6976
pISSN - 0168-6445
DOI - 10.1093/femsre/fuv014
Subject(s) - biology , transfer rna , base pair , pairing , computational biology , genetics , rna , base (topology) , identification (biology) , evolutionary biology , gene , ecology , physics , mathematical analysis , superconductivity , mathematics , quantum mechanics
The increasing numbers of characterized base-pairing small RNAs (sRNAs) and the identification of these regulators in a broad range of bacteria are allowing comparisons between species and explorations of sRNA evolution. In this review, we describe some examples of trans-encoded base-pairing sRNAs that are species-specific and others that are more broadly distributed. We also describe examples of sRNA orthologs where different features are conserved. These examples provide the background for a discussion of mechanisms of sRNA evolution and selective pressures on the sRNAs and their mRNA target(s).

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