Anti-tick-borne encephalitis (TBE) virus neutralizing antibodies dynamics in natural infections versus vaccination | Zendy

Maria Elena Remoli | Zendy; Antonella Marchi | Zendy; Claudia Fortuna | Zendy; Eleonora Benedetti | Zendy; Giada Minelli | Zendy; Cristiano Fiorentini | Zendy; Rosanna Mel | Zendy; Giulietta Venturi | Zendy; Maria Grazia Ciufolini | Zendy

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Anti-tick-borne encephalitis (TBE) virus neutralizing antibodies dynamics in natural infections versus vaccination

Author(s) -

Maria Elena Remoli,

Antonella Marchi,

Claudia Fortuna,

Eleonora Benedetti,

Giada Minelli,

Cristiano Fiorentini,

Rosanna Mel,

Giulietta Venturi,

Maria Grazia Ciufolini

Publication year - 2014

Publication title -

pathogens and disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.983

H-Index - 105

ISSN - 2049-632X

DOI - 10.1093/femspd/ftu002

Subject(s) - virology , tick borne encephalitis , neutralizing antibody , antibody , encephalitis , vaccination , virus , titer , tick borne encephalitis virus , tick , biology , immunology , medicine

Tick-borne encephalitis (TBE) virus infection elicits a life-long lasting protection. However, little is known about the neutralizing antibodies titres following natural infection. In this study, subjects with past TBE disease (n = 62) were analysed for the presence and titre of anti-TBE neutralizing antibodies, and compared with a vaccinated cohort (n = 101). Neutralizing antibody titres were higher in individuals with past TBE and did not show an age-dependent decrease when compared with vaccinees.

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