Small extracellular particles with big potential for horizontal gene transfer: membrane vesicles and gene transfer agents
Author(s) -
Marc P. Grüll,
Martin E. Mulligan,
Andrew S. Lang
Publication year - 2018
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1093/femsle/fny192
Subject(s) - horizontal gene transfer , biogenesis , extracellular , gene transfer , extracellular vesicles , gene , bacteria , microbiology and biotechnology , vesicle , biology , chemistry , membrane , biophysics , genetics , genome
Bacteria are known to release different types of particles that serve various purposes such as the processing of metabolites, communication, and the transfer of genetic material. One of the most interesting aspects of the production of such particles is the biogenesis and trafficking of complex particles that can carry DNA, RNA, proteins or toxins into the surrounding environment to aid in bacterial survival or lead to gene transfer. Two important bacterial extracellular complexes are membrane vesicles and gene transfer agents. In this review, we will discuss the production, contents and functions of these two types of particles as related to their abilities to facilitate horizontal gene transfer.
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