A yeast for all seasons – Is Pichia pastoris a suitable chassis organism for future bioproduction? | Zendy

Brigitte Gasser | Zendy; Diethard Mattanovich | Zendy

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A yeast for all seasons – Is Pichia pastoris a suitable chassis organism for future bioproduction?

Author(s) -

Brigitte Gasser,

Diethard Mattanovich

Publication year - 2018

Publication title -

fems microbiology letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.899

H-Index - 151

eISSN - 1574-6968

pISSN - 0378-1097

DOI - 10.1093/femsle/fny181

Subject(s) - pichia pastoris , bioproduction , organism , yeast , chassis , model organism , synthetic biology , biology , computational biology , recombinant dna , microbiology and biotechnology , biochemistry , genetics , gene , engineering , structural engineering

The methylotrophic yeast Pichia pastoris (Komagataella spp.) is well established as a host for recombinant protein production. Since a few years it has also been subject to metabolic engineering to produce a diversity of biochemicals. Based on these developments we discuss here why P. pastoris is a suitable future chassis organism for synthetic biology, and we provide a roadmap for a community effort towards this aim.

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