First report of a Klebsiella pneumoniae ST466 strain causing neonatal sepsis harbouring the blaCTX-M-15 gene in Rabat, Morocco | Zendy

Victoria Ballén | Zendy; Emma Sáez-López | Zendy; Rachid Benmessaoud | Zendy; H. Tligui | Zendy; Hassan El Alami | Zendy; Amina Barkat | Zendy; Meryem Kabiri | Zendy; Cinta Moraleda | Zendy; Rachid Bezad | Zendy; Jordi Vilà | Zendy; Jordi Bosch | Zendy; Quique Bassat | Zendy; Sara M. Soto | Zendy

Open Access

First report of a Klebsiella pneumoniae ST466 strain causing neonatal sepsis harbouring the blaCTX-M-15 gene in Rabat, Morocco

Author(s) -

Victoria Ballén,

Emma Sáez-López,

Rachid Benmessaoud,

H. Tligui,

Hassan El Alami,

Amina Barkat,

Meryem Kabiri,

Cinta Moraleda,

Rachid Bezad,

Jordi Vilà,

Jordi Bosch,

Quique Bassat,

Sara M. Soto

Publication year - 2015

Publication title -

fems microbiology letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.899

H-Index - 151

eISSN - 1574-6968

pISSN - 0378-1097

DOI - 10.1093/femsle/fnu026

Subject(s) - klebsiella pneumoniae , neonatal sepsis , sepsis , medicine , microbiology and biotechnology , antimicrobial , bacilli , urine , immunology , biology , bacteria , gene , escherichia coli , biochemistry , genetics

Klebsiella pneumoniae is one of the Gram-negative bacilli most commonly found in urine of pregnant women and causing neonatal sepsis. The aim of this study was to analyse in terms of epidemiology and antimicrobial resistance of 23 K. pneumoniae isolates collected from vaginal swabs or urine of pregnant women, from pharyngeal and ear swabs of apparently healthy newborns and from peripheral cultures and hemocultures of newborns with suspected invasive neonatal infection in Rabat, Morocco. The prevalence of K. pneumoniae was 0.6 and 0.9% among pregnant women and neonates, respectively. These strains showed lower antimicrobial resistance levels regarding the developed countries. Thus, only one strain from a neonate presented an ESBL. This is the first report of a K. pneumoniae strain causing neonatal sepsis harbouring the blaCTX-M-15 gene in an IncFII plasmid and belonging to ST466 in this area.

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