Stroke and bleeding risk scores in patients with atrial fibrillation and valvular heart disease: evaluating ‘valvular heart disease’ in a nationwide cohort study | Zendy

Gregory Y.H. Lip | Zendy; Martin Jensen | Zendy; Line Melgaard | Zendy; Flemming Skjøth | Zendy; Peter Brønnum Nielsen | Zendy; Torben Bjerregaard Larsen | Zendy

Open Access

Stroke and bleeding risk scores in patients with atrial fibrillation and valvular heart disease: evaluating ‘valvular heart disease’ in a nationwide cohort study

Author(s) -

Gregory Y.H. Lip,

Martin Jensen,

Line Melgaard,

Flemming Skjøth,

Peter Brønnum Nielsen,

Torben Bjerregaard Larsen

Publication year - 2018

Publication title -

ep europace

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.119

H-Index - 102

eISSN - 1532-2092

pISSN - 1099-5129

DOI - 10.1093/europace/euy151

Subject(s) - medicine , atrial fibrillation , valvular heart disease , stroke (engine) , cardiology , cohort , stenosis , cha2ds2–vasc score , heart disease , ischemic stroke , mechanical engineering , ischemia , engineering

Substantial interest has been directed towards stroke risk stratification in patients with atrial fibrillation (AF) but prior studies have focused on AF without significant valvular heart disease (VHD), so-called 'non-valvular AF'. A formal validation exercise addressing stroke risks in relation to the CHA2DS2-VASc risk factor(s) in AF patients with VHD is lacking. Also, the use of the HAS-BLED score in anticoagulated patients with VHD has not been previously studied. The aim of this study was to investigate stroke and bleeding rates in AF patients with VHD in relation to the CHA2DS2-VASc and HAS-BLED scores.

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