Open AccessPulmonary vein isolation by radiosurgery: implications for non-invasive treatment of atrial fibrillation
Author(s) -
Frank Bode,
Oliver Blanck,
Maximilian Gebhard,
Peter Hunold,
M. Großherr,
Sebastián Brandt,
Reinhard Vonthein,
Hölger Thiele,
Juergen Dunst,
Dirk Rades
Publication year - 2015
Publication title -
ep europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/euu406
Subject(s) - medicine , pulmonary vein , atrial fibrillation , ablation , radiosurgery , catheter ablation , cardiology , nuclear medicine , cardiac ablation , radiology , radiation therapy
Electrical isolation of the pulmonary veins (PVs) has been established in clinical routine as a curative treatment for atrial fibrillation (AF). While catheter ablation carries procedural risks, radiosurgery might be able to non-invasively induce lesions at the PV ostia to block veno-atrial electrical conduction. This porcine feasibility and dose escalation study determined the effect of radiosurgery on electrophysiologic properties of the left atrial-PV junction.
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