Open AccessA bilayer model of human atria: mathematical background, construction, and assessment
Author(s) -
Simon Labarthe,
Jason D. Bayer,
Yvès Coudière,
Jacques Henry,
Hubert Cochet,
Pierre Jaı̈s,
Edward J. Vigmond
Publication year - 2014
Publication title -
europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/euu256
Subject(s) - crista terminalis , bilayer , biological system , biophysics , coupling (piping) , dissociation (chemistry) , monolayer , biomedical engineering , mechanics , medicine , physics , cardiology , chemistry , materials science , nanotechnology , biology , ablation , membrane , catheter ablation , biochemistry , metallurgy
Atrial numerical modelling has generally represented the organ as either a surface or tissue with thickness. While surface models have significant computational advantages over tissue models, they cannot fully capture propagation patterns seen in vivo, such as dissociation of activity between endo- and epicardium. We introduce an intermediate representation, a bilayer model of the human atria, which is capable of recreating recorded activation patterns.