Quality-of-life benefits of catheter ablation of persistent atrial fibrillation: a reanalysis of data from the SARA study | Zendy

Gareth Wynn | Zendy; Moloy Das | Zendy; Laura Bonnett | Zendy; D.P. Sen Gupta | Zendy

Open Access

Quality-of-life benefits of catheter ablation of persistent atrial fibrillation: a reanalysis of data from the SARA study

Author(s) -

Gareth Wynn,

Moloy Das,

Laura Bonnett,

D.P. Sen Gupta

Publication year - 2014

Publication title -

ep europace

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.119

H-Index - 102

eISSN - 1532-2092

pISSN - 1099-5129

DOI - 10.1093/europace/euu154

Subject(s) - medicine , atrial fibrillation , quality of life (healthcare) , randomized controlled trial , catheter ablation , ablation , cardiology , clinical endpoint , physical therapy , nursing

The recently published SARA study was a prospective, multi-centre randomized controlled trial that compared CA to antiarrhythmic drug therapy (ADT) in 146 patients with persistent atrial fibrillation (AF). The study found that recurrence of AF or atrial flutter occurred significantly less often in the CA arm compared to the ADT arm (29.6% vs. 56.3%, p = 0.002). Despite this clear superiority in terms of efficacy, the authors were not able to demonstrate a corresponding Quality of Life (QoL) improvement. We sought to investigate this apparent disparity using alternative analytical methods.

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