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Mechanistic insights into hypothermic ventricular fibrillation: the role of temperature and tissue size
Author(s) -
Simonetta Filippi,
Alessio Gizzi,
Christian Cherubini,
Stefan Luther,
Flavio H. Fenton
Publication year - 2014
Publication title -
ep europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/euu031
Subject(s) - medicine , hypothermia , intracardiac injection , ventricular fibrillation , cardiology , resuscitation , fibrillation , ventricular function , intensive care medicine , atrial fibrillation , anesthesia
Hypothermia is well known to be pro-arrhythmic, yet it has beneficial effects as a resuscitation therapy and valuable during intracardiac surgeries. Therefore, we aim to study the mechanisms that induce fibrillation during hypothermia. A better understanding of the complex spatiotemporal dynamics of heart tissue as a function of temperature will be useful in managing the benefits and risks of hypothermia.

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