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Increased amount of interstitial fibrosis predicts ventricular arrhythmias, and is associated with reduced myocardial septal function in patients with obstructive hypertrophic cardiomyopathy
Author(s) -
Vibeke Marie Almaas,
Kristina H. Haugaa,
Erik H. Strøm,
Helge Scott,
Christen P. Dahl,
Trond P. Leren,
Odd Geiran,
Knut Endresen,
Thor Edvardsen,
Svend Aakhus,
Jan Amlie
Publication year - 2013
Publication title -
ep europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/eut028
Subject(s) - medicine , cardiology , hypertrophic cardiomyopathy , ventricular tachycardia , fibrosis , myocardial fibrosis , population , cardiomyopathy , coronary artery disease , heart failure , environmental health
Reduced echocardiographic strain is associated with ventricular arrhythmias in hypertrophic cardiomyopathy (HCM) patients. The aim of this cross-sectional study was to investigate which type of histological fibrosis contributes to ventricular arrhythmias and reduced septal longitudinal strain, in obstructive HCM-patients with or without additional coronary artery disease (CAD) and/or hypertension (HT).

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