Role of nitric oxide and oxidative stress in a sheep model of persistent atrial fibrillation | Zendy

Ilse Lenaerts | Zendy; Ronald B. Driesen | Zendy; Nerea Hermida Blanco | Zendy; Patricia Holemans | Zendy; Hein Heidbüchel | Zendy; Stefan Janssens | Zendy; JeanLuc Balligand | Zendy; Karin R. Sipido | Zendy; Rik Willems | Zendy

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Role of nitric oxide and oxidative stress in a sheep model of persistent atrial fibrillation

Author(s) -

Ilse Lenaerts,

Ronald B. Driesen,

Nerea Hermida Blanco,

Patricia Holemans,

Hein Heidbüchel,

Stefan Janssens,

JeanLuc Balligand,

Karin R. Sipido,

Rik Willems

Publication year - 2013

Publication title -

ep europace

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.119

H-Index - 102

eISSN - 1532-2092

pISSN - 1099-5129

DOI - 10.1093/europace/eut012

Subject(s) - oxidative stress , peroxynitrite , nitrotyrosine , medicine , endocrinology , nadph oxidase , superoxide dismutase , nicotinamide adenine dinucleotide phosphate , nitric oxide , nitric oxide synthase , oxidase test , superoxide , nos1 , biochemistry , enzyme , biology

Oxidative stress can modulate nitric oxide (NO) signalling pathways. Both pathways have been shown to be involved in the pathophysiology of atrial fibrillation (AF), but data are conflicting. We aimed to characterize the NO-pathway and its relation to oxidative stress in persistent AF in a sheep model.

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