Adenosine plus dipyridamole: a novel strategy to enhance adenosine-induced conduction recovery after pulmonary vein isolation | Zendy

Tom De Potter | Zendy; Martin Eisenberger | Zendy; Conor McCann | Zendy; P. Peytchev | Zendy; P Geelen | Zendy

Open Access

Adenosine plus dipyridamole: a novel strategy to enhance adenosine-induced conduction recovery after pulmonary vein isolation

Author(s) -

Tom De Potter,

Martin Eisenberger,

Conor McCann,

P. Peytchev,

P Geelen

Publication year - 2012

Publication title -

ep europace

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.119

H-Index - 102

eISSN - 1532-2092

pISSN - 1099-5129

DOI - 10.1093/europace/eus159

Subject(s) - adenosine , medicine , dipyridamole , pulmonary vein , anesthesia , bolus (digestion) , atrial fibrillation , cardiology

Intravenous administration of adenosine after a pulmonary vein (PV) isolation procedure can unmask residual, so-called 'dormant', conduction that would otherwise remain unnoticed. Elimination of these dormant potentials is challenging because of the transient effect of adenosine, often requiring repeated injections. We tested the hypothesis that dipyridamole, a drug which inhibits adenosine deamination, can provoke longer-lasting unmasking of dormant conduction.

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