Reduced connexin40 protein expression in the right atrial appendage of patients bearing the minor connexin40 allele (−44 G → A) | Zendy

SevastiMaria Chaldoupi | Zendy; Lisette E. G. Hubens | Zendy; Daan A. Smit Duijzentkunst | Zendy; Leonie van Stuijvenberg | Zendy; Marti F.A. Bierhuizen | Zendy; Egidius E.H.L. van Aarnhem | Zendy; Marcel Nelen | Zendy; Jacques M.T. de Bakker | Zendy; Richard N.W. Hauer | Zendy; Harold V.M. van Rijen | Zendy; Peter Loh | Zendy; Toon A.B. van Veen | Zendy

Open Access

Reduced connexin40 protein expression in the right atrial appendage of patients bearing the minor connexin40 allele (−44 G → A)

Author(s) -

SevastiMaria Chaldoupi,

Lisette E. G. Hubens,

Daan A. Smit Duijzentkunst,

Leonie van Stuijvenberg,

Marti F.A. Bierhuizen,

Egidius E.H.L. van Aarnhem,

Marcel Nelen,

Jacques M.T. de Bakker,

Richard N.W. Hauer,

Harold V.M. van Rijen,

Peter Loh,

Toon A.B. van Veen

Publication year - 2012

Publication title -

ep europace

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.119

H-Index - 102

eISSN - 1532-2092

pISSN - 1099-5129

DOI - 10.1093/europace/eus047

Subject(s) - medicine , cardiology , atrial appendage , appendage , minor allele frequency , atrial fibrillation , anatomy , allele , gene , allele frequency , genetics , sinus rhythm , biology

The occurrence of connexin40 (Cx40) minor polymorphism (-44 G → A) was increased in patients with idiopathic atrial fibrillation (AF), although its effect on atrial Cx40 protein expression is unknown. We aimed to evaluate whether alterations in Cx40 are directly linked to the development of AF, we studied the effect of this polymorphism on Cx40 expression and distribution in patients without any history of AF and in patients who developed post-operative AF.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research