Cardiac resynchronization therapy may improve symptoms of congestive heart failure in patients without electrical or mechanical dyssynchrony
Author(s) -
Alireza Nazeri,
Ali Massumi,
Abdi Rasekh,
Mohammad Saeed,
Christopher J. Frank,
James M. Wilson,
José A. López,
Mehdi Razavi
Publication year - 2008
Publication title -
ep europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/eun326
Subject(s) - medicine , cardiology , cardiac resynchronization therapy , heart failure , ejection fraction , mitral regurgitation , ventricular dyssynchrony , natriuretic peptide , cardiomyopathy
Cardiac resynchronization therapy (CRT) has reportedly not been effective in the absence of electrical or mechanical dyssynchrony. We present six patients with severe left ventricular (LV) dilation, mitral regurgitation (MR), and non-ischaemic cardiomyopathy who underwent CRT. We assessed the effects of CRT on LV ejection fraction (EF), LV dimensions, mitral valve regurgitant fraction (RF), pulmonary arterial pressures (PAP), and serum levels of B-natriuretic peptide (BNP).
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