Open AccessCardiac repolarization during hypoglycaemia in type 1 diabetes: impact of basal renin-angiotensin system activity
Author(s) -
R. Due-Andersen,
Thomas Høi-Hansen,
Charlotte Larroudé,
Niels Vidiendal Olsen,
Jørgen K. Kanters,
Frans Boomsma,
Ulrik PedersenBjergaard,
Birger Thorsteinsson
Publication year - 2008
Publication title -
ep europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/eun137
Subject(s) - medicine , renin–angiotensin system , basal (medicine) , cardiology , repolarization , diabetes mellitus , pathogenesis , sudden cardiac death , endocrinology , blood pressure , electrophysiology
Hypoglycaemia-induced cardiac arrhythmias may be involved in the pathogenesis of the 'dead-in-bed syndrome' in patients with type 1 diabetes. Evidence suggests that the renin-angiotensin system (RAS) influences the occurrence of arrhythmias. The aim of this study was to explore if basal RAS activity affects cardiac repolarization during hypoglycaemia, thereby potentially carrying prognostic information on risk of the 'dead-in-bed syndrome'.
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