Modelling cardiac fibroblasts: interactions with myocytes and their impact on impulse propagation
Author(s) -
Vincent Jacquemet,
Craig S. Henriquez
Publication year - 2007
Publication title -
ep europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/eum207
Subject(s) - myocyte , fibroblast , cardiac myocyte , coupling (piping) , atrial myocytes , biophysics , medicine , cellular model , impulse (physics) , cell culture , physics , biology , materials science , genetics , metallurgy , quantum mechanics
Existence of myocyte-fibroblast coupling in the human heart is still a controversial question. This study aims at investigating in a biophysical model how much coupling would be necessary to perturb significantly the electrical propagation of the cardiac impulse.
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