Open AccessAcute myocardial infarction with no obstructive coronary atherosclerosis: mechanisms and management
Author(s) -
Giampaolo Niccoli,
Giancarla Scalone,
Filippo Crea
Publication year - 2014
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehu469
Subject(s) - medicine , myocardial infarction , cardiology , coronary atherosclerosis , coronary angiography , risk stratification , acute coronary syndrome , pathogenesis , coronary artery disease
Myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5 and 25% of all MIs. The prognosis is extremely variable, depending on the causes of MINOCA. Clinical history, echocardiography, coronary angiography, and left ventriculography represent the first-level diagnostic investigations. Nevertheless, additional tests are required in order to establish its specific cause, thus allowing an appropriate risk stratification and treatment. We review pathogenesis, diagnosis, prognosis, and therapy of MINOCA and propose an algorithm for its management.