Circulating angiopoietins and cardiovascular mortality in cardiogenic shock | Zendy

Andreas Link | Zendy; Janine Pöss | Zendy; Ranja Rbah | Zendy; Christine Barth | Zendy; Luisa Feth | Zendy; Simina Selejan | Zendy; Michael Böhm | Zendy

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Circulating angiopoietins and cardiovascular mortality in cardiogenic shock

Author(s) -

Andreas Link,

Janine Pöss,

Ranja Rbah,

Christine Barth,

Luisa Feth,

Simina Selejan,

Michael Böhm

Publication year - 2013

Publication title -

european heart journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.336

H-Index - 293

eISSN - 1522-9645

pISSN - 0195-668X

DOI - 10.1093/eurheartj/ehs487

Subject(s) - medicine , cardiogenic shock , cardiology , hemodynamics , shock (circulatory) , angiopoietin , angiopoietin 2 , endothelial activation , endothelium , myocardial infarction , vascular endothelial growth factor , vegf receptors

Vascular integrity is disturbed in shock contributing to clinical appearance and serious outcomes. While angiopoietin (Ang)-1 protects from vascular inflammation and leakage, Ang-2 disrupts endothelial barrier function. The imbalance of Ang-1 and Ang-2, their association to haemodynamic deterioration, and their prognostic relevance are not known and, thus, were prospectively evaluated in patients with cardiogenic shock (CS) in this study.

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