Urgent surgery compared with fibrinolytic therapy for the treatment of left-sided prosthetic heart valve thrombosis: a systematic review and meta-analysis of observational studies | Zendy

Ganesan Karthikeyan | Zendy; Nagendra Boopathy Senguttuvan | Zendy; Jo Joseph | Zendy; Niveditha Devasenapathy | Zendy; Vinay K. Bahl | Zendy; Balram Airan | Zendy

Open Access

Urgent surgery compared with fibrinolytic therapy for the treatment of left-sided prosthetic heart valve thrombosis: a systematic review and meta-analysis of observational studies

Author(s) -

Ganesan Karthikeyan,

Nagendra Boopathy Senguttuvan,

Jo Joseph,

Niveditha Devasenapathy,

Vinay K. Bahl,

Balram Airan

Publication year - 2013

Publication title -

european heart journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.336

H-Index - 293

eISSN - 1522-9645

pISSN - 0195-668X

DOI - 10.1093/eurheartj/ehs486

Subject(s) - medicine , observational study , meta analysis , thrombosis , fibrinolytic therapy , heart valve , cardiology , surgery , fibrinolysis

Left-sided prosthetic valve thrombosis (PVT) occurs frequently in developing countries and causes major morbidity and mortality. Fibrinolytic therapy (FT) is most commonly used as treatment, but increases the risk of stroke and bleeding. Urgent surgery may be more efficacious and cause fewer complications. Our aim was to compare the efficacy and safety of urgent surgery and FT for the treatment of left-sided PVT.

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