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Evaluation of early percutaneous coronary intervention vs. standard therapy after fibrinolysis for ST-segment elevation myocardial infarction: contribution of weighting the composite endpoint
Author(s) -
Jeffrey A. Bakal,
Cynthia M. Westerhout,
Warren J. Cantor,
Francisco FernándezAvilés,
Robert C. Welsh,
D. Fitchett,
Shaun G. Goodman,
Paul W. Armstrong
Publication year - 2012
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehs438
Subject(s) - medicine , percutaneous coronary intervention , fibrinolysis , cardiology , myocardial infarction , st segment
The selection of optimal endpoints for cardiovascular clinical trials continues to be challenging. We examined an alternative interpretation of a series of trials when the individual event severity is considered.

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