Evaluation of early percutaneous coronary intervention vs. standard therapy after fibrinolysis for ST-segment elevation myocardial infarction: contribution of weighting the composite endpoint
Author(s) -
Jeffrey A. Bakal,
Cynthia M. Westerhout,
Warren J. Cantor,
Francisco FernándezAvilés,
Robert C. Welsh,
D. Fitchett,
Shaun G. Goodman,
Paul W. Armstrong
Publication year - 2012
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehs438
Subject(s) - medicine , percutaneous coronary intervention , fibrinolysis , cardiology , myocardial infarction , st segment
The selection of optimal endpoints for cardiovascular clinical trials continues to be challenging. We examined an alternative interpretation of a series of trials when the individual event severity is considered.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom