Influence of 23 coronary artery disease variants on recurrent myocardial infarction or cardiac death: the GRACE Genetics Study
Author(s) -
Els Wauters,
Kathryn Carruthers,
Ian Buysschaert,
Donald R. Dunbar,
Gilian Peuteman,
Ann Belmans,
Andrzej Budaj,
Frans Van de Werf,
Diether Lambrechts,
Keith A.A. Fox
Publication year - 2012
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehs389
Subject(s) - medicine , myocardial infarction , coronary artery disease , cardiology , genome wide association study , disease , single nucleotide polymorphism , genetics , genotype , gene , biology
A pooled analysis of 14 genome-wide association studies revealed 23 susceptibility loci for coronary artery disease (CAD), thereby providing the most comprehensive genetic blueprint of CAD susceptibility. Here, we evaluated whether these 23 loci also predispose to recurrent myocardial infarction (MI) or cardiac death following an acute coronary syndrome (ACS).
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