Imaging of myocardial infarction using ultrasmall superparamagnetic iron oxide nanoparticles: a human study using a multi-parametric cardiovascular magnetic resonance imaging approach
Author(s) -
Ali Yılmaz,
Michael A. Dengler,
Heiko van der Kuip,
Handan Yıldız,
Sabine Rösch,
Siegfried Klumpp,
Karin Klingel,
Reinhard Kandolf,
Xavier Helluy,
KarlHeinz Hiller,
Peter M. Jakob,
Udo Sechtem
Publication year - 2012
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehs366
Subject(s) - ferumoxytol , medicine , myocardial infarction , magnetic resonance imaging , cardiology , cardiac magnetic resonance imaging , nuclear medicine , radiology
The purpose of this clinical trial was to investigate whether cardiovascular magnetic resonance imaging (CMR) using ferumoxytol (Feraheme™, FH), an ultrasmall superparamagnetic iron oxide nanoparticle (USPIO), allows more detailed characterization of infarct pathology compared with conventional gadolinium-based necrosis/fibrosis imaging in patients with acute myocardial infarction.
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