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Liver function abnormalities, clinical profile, and outcome in acute decompensated heart failure
Author(s) -
Maria Nikolaou,
John Parissis,
Mehmet Birhan Yılmaz,
MarieFrance Seronde,
Matti Kivikko,
Sai͏̈d Laribi,
Cathérine PaugamBurtz,
Dandan Cai,
Pasi Pohjanjousi,
Pierre-François Laterre,
Nicolas Deye,
Pentti Põder,
Alain CohenSolal,
Alexandre Mebazaa
Publication year - 2012
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehs332
Subject(s) - acute decompensated heart failure , medicine , levosimendan , elevated transaminases , heart failure , cholestasis , liver function tests , gastroenterology , spontaneous bacterial peritonitis , aspartate transaminase , cardiology , cirrhosis , alkaline phosphatase , biochemistry , chemistry , enzyme
The aim of this study was to assess the prevalence of abnormal liver function tests (LFTs) and the associated clinical profile and outcome(s) in acute decompensated heart failure (ADHF) patients. Alteration in LFTs is a recognized feature of ADHF, but prevalence and outcomes data from a broad contemporary cohort of ADHF are scarce and the mechanism(s) of ADHF-induced cholestasis is unknown.

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