Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction | Zendy

Yin Liu | Zendy; Xiangru Lu | Zendy; Fu-Li Xiang | Zendy; Robert E. Poelmann | Zendy; Adriana C. Gittenberger–de Groot | Zendy; Jeffrey Robbins | Zendy; Qingping Feng | Zendy

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Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction

Author(s) -

Yin Liu,

Xiangru Lu,

Fu-Li Xiang,

Robert E. Poelmann,

Adriana C. Gittenberger–de Groot,

Jeffrey Robbins,

Qingping Feng

Publication year - 2012

Publication title -

european heart journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.336

H-Index - 293

eISSN - 1522-9645

pISSN - 0195-668X

DOI - 10.1093/eurheartj/ehs306

Subject(s) - medicine , coronary arteries , nitric oxide synthase , myocardial infarction , cardiology , nitric oxide , hypoplasia , artery , coronary artery disease , endocrinology

Hypoplastic coronary artery disease is a rare congenital abnormality that is associated with sudden cardiac death. However, molecular mechanisms responsible for this disease are not clear. The aim of the present study was to assess the role of nitric oxide synthase-3 (NOS3) in the pathogenesis of hypoplastic coronary arteries.

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