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Intracoronary microparticles and microvascular obstruction in patients with ST elevation myocardial infarction undergoing primary percutaneous intervention
Author(s) -
Italo Porto,
Luigi M. Biasucci,
Giovanni Luigi De Maria,
Antonio Maria Leone,
Giampaolo Niccoli,
Francesco Burzotta,
Carlo Trani,
Alessandra Tritarelli,
Rocco Vergallo,
Giovanna Liuzzo,
Filippo Crea
Publication year - 2012
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehs065
Subject(s) - medicine , timi , cardiology , myocardial infarction , percutaneous coronary intervention , culprit , thrombus , thrombolysis , artery
Microparticles (MP) are cell-derived fragments known to be increased in the blood of patients with acute coronary syndromes. We aimed to assess, in ST elevation myocardial infarction (STEMI), the systemic and local (in the culprit coronary artery) levels of platelet-derived MP (PMP, CD42+CD31+) and endothelial-derived MP (EMP, CD42-CD31+) and their relation to indexes of microvascular obstruction (MVO).

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