Safety and efficacy of a pharmaco-invasive reperfusion strategy in rural ST-elevation myocardial infarction patients with expected delays due to long-distance transfers
Author(s) -
David M. Larson,
Sue Duval,
Scott W. Sharkey,
Ross Garberich,
James D. Madison,
Peter J. Stokman,
T. Dirks,
R. K. Westin,
James L. Harris,
Timothy D. Henry
Publication year - 2011
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehr403
Subject(s) - medicine , conventional pci , percutaneous coronary intervention , myocardial infarction , clopidogrel , reperfusion therapy , timi , cardiology , fibrinolysis , aspirin , st elevation , fibrinolytic agent , emergency medicine , tissue plasminogen activator
To determine the safety and efficacy of a pharmaco-invasive reperfusion strategy utilizing half-dose fibrinolysis combined with transfer for immediate percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) patients presenting to remote rural hospitals. Primary PCI is preferred for STEMI if performed in a timely manner. However, <20% of STEMI patients transferred for PCI in the USA have door-to-balloon times <2 h.
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