Open AccessPlasma levels of thromboxane A2 on admission are associated with no-reflow after primary percutaneous coronary intervention
Author(s) -
Giampaolo Niccoli,
Simona Giubilato,
Eleonora Russo,
Cristina Spaziani,
Andrea Leo,
Italo Porto,
Antonio Maria Leone,
Francesco Burzotta,
Silvia Riondino,
Fabio M. Pulcinelli,
Luigi M. Biasucci,
Filippo Crea
Publication year - 2008
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehn325
Subject(s) - medicine , timi , percutaneous coronary intervention , cardiology , thromboxane a2 , myocardial infarction , conventional pci , platelet
Thromboxane A2 (TXA2) is a key mediator of platelet activation and aggregation, and an important mediator of platelet-induced coronary artery constriction. We sought to investigate whether baseline plasma levels of TXA2 are associated with coronary no-reflow after primary percutaneous coronary intervention (PPCI).