Open AccessSpironolactone reduces fibrosis of dilated atria during heart failure in rats with myocardial infarction
Author(s) -
Paul Milliez,
N. Deangelis,
Catherine RückerMartin,
Antoine Leenhardt,
Éric Vicaut,
Estelle Robidel,
Philippe Beaufils,
Claude Delcayre,
Stéphane N. Hatem
Publication year - 2005
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehi478
Subject(s) - medicine , spironolactone , cardiology , heart failure , myocardial infarction , dilated cardiomyopathy
Congestive heart failure (CHF) is associated with severe structural changes of atria, contributing to impaired atrial function and the risk of arrhythmia. This study investigated the effects of CHF treatments on atrial remodelling.