Open AccessComparative analysis of the activity and content of different streptokinase preparations
Author(s) -
P. Hermentin,
Thomas Cuesta-Linker,
Joerg Weisse,
KarlHeinz Schmidt,
Marion Knorst,
Michael Scheld,
Michael Thimme
Publication year - 2005
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehi093
Subject(s) - streptokinase , medicine , chromogenic , recombinant dna , chromatography , polyacrylamide gel electrophoresis , pharmacology , biochemistry , enzyme , chemistry , myocardial infarction , gene
The dosage of fibrinolytic agents such as streptokinase must be controlled carefully to maximize therapeutic activity while avoiding adverse effects. Therefore, the integrity and activity of streptokinase products is likely to be clinically relevant. This study was conducted to compare the in vitro characteristics of different streptokinase preparations.