Illness in breastfeeding infants relates to concentration of lactoferrin and secretory Immunoglobulin A in mother’s milk | Zendy

Alicia A. Breakey | Zendy; Katie Hinde | Zendy; Claudia Valeggia | Zendy; Allison Sinofsky | Zendy; Peter T. Ellison | Zendy

Open Access

Illness in breastfeeding infants relates to concentration of lactoferrin and secretory Immunoglobulin A in mother’s milk

Author(s) -

Alicia A. Breakey,

Katie Hinde,

Claudia Valeggia,

Allison Sinofsky,

Peter T. Ellison

Publication year - 2015

Publication title -

evolution medicine and public health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 22

ISSN - 2050-6201

DOI - 10.1093/emph/eov002

Subject(s) - lactoferrin , breastfeeding , antibody , formula feeding , secretory iga , lactation , immunoglobulin a , medicine , food science , immunoglobulin g , immunology , biology , pregnancy , pediatrics , biochemistry , genetics

This study aims to better understand the relationship between immune compounds in human milk and infant health. We hypothesized that the concentration of immune compounds in milk would relate to infant illness symptoms according to two possible theoretical paradigms. In the 'protective' paradigm, high concentrations of immune compounds prevent infant illness. The converse, the 'responsive' framework, posits that concentrations of immune compounds are elevated in response to infection.

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