Vitamin D, folate, and potential early lifecycle environmental origin of significant adult phenotypes | Zendy

Mark Lucock | Zendy; Zoë Yates | Zendy; Charlotte Martin | Zendy; JeongHwa Choi | Zendy; Lyndell Boyd | Zendy; Sa Tang | Zendy; Nenad Naumovski | Zendy; J. E. Furst | Zendy; Paul D. Roach | Zendy; Nina G. Jablonski | Zendy; George Chaplin | Zendy; Martin Veysey | Zendy

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Vitamin D, folate, and potential early lifecycle environmental origin of significant adult phenotypes

Author(s) -

Mark Lucock,

Zoë Yates,

Charlotte Martin,

JeongHwa Choi,

Lyndell Boyd,

Sa Tang,

Nenad Naumovski,

J. E. Furst,

Paul D. Roach,

Nina G. Jablonski,

George Chaplin,

Martin Veysey

Publication year - 2014

Publication title -

evolution medicine and public health

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 22

ISSN - 2050-6201

DOI - 10.1093/emph/eou013

Subject(s) - calcitriol receptor , phenotype , folate receptor , vitamin d and neurology , biology , pregnancy , gene , nuclear receptor , first trimester , vitamin , sun exposure , physiology , genetics , medicine , endocrinology , fetus , cancer , cancer cell , dermatology , transcription factor

Vitamin D and folate are highly UV sensitive, and critical for maintaining health throughout the lifecycle. This study examines whether solar irradiance during the first trimester of pregnancy influences vitamin D receptor (VDR) and nuclear folate gene variant occurrence, and whether affected genes influence late-life biochemical/clinical phenotypes.

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