Open AccessGenome organization and the role of centromeres in evolution of the erythroleukaemia cell line HEL
Author(s) -
Ruth N. MacKin,
Meaghan Wall,
Adrian Zordan,
Srilakshmi Nutalapati,
Bruce Mercer,
Joanne Peverall,
Lynda J. Campbell
Publication year - 2013
Publication title -
evolution medicine and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 22
ISSN - 2050-6201
DOI - 10.1093/emph/eot020
Subject(s) - centromere , biology , genome , genetics , genomic organization , line (geometry) , cell culture , computational biology , evolutionary biology , microbiology and biotechnology , chromosome , gene , geometry , mathematics
The human erythroleukaemia (HEL) cell line has a highly rearranged genome. We matched whole chromosome analysis with cytogenomic microarray data to build a detailed description of these rearrangements.
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