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Recombinant osteoprotegerin effects during orthodontic movement in a rat model
Author(s) -
Felipe J. Fernández-González,
Aránzazu Cañigral,
José L. López-Caballo,
Aritza BrizuelaVelasco,
Teresa Cobo,
Félix de Carlos Villafranca,
Iván Suazo Galdames,
Yurena Pérez-González,
José A. Vega
Publication year - 2015
Publication title -
european journal of orthodontics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.252
H-Index - 84
eISSN - 1460-2210
pISSN - 0141-5387
DOI - 10.1093/ejo/cjv056
Subject(s) - osteoprotegerin , molar , periodontal fiber , immunohistochemistry , rankl , receptor , vimentin , chemistry , medicine , dentistry , endocrinology , activator (genetics)
Anchorage is one of the most challenging sides in orthodontics. The use of biological modulators that inhibit osteoclasts could be a solution to address these problems and provide new adjunctive approaches. The aim of this study was to assess the effectiveness of recombinant osteoprotegerin fusion protein (OPG-Fc) in orthodontic anchorage.

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