Effect of interleukin-4 on orthodontic tooth movement and associated root resorption | Zendy

Zaki Hakami | Zendy; Hideki Kitaura | Zendy; Keisuke Kimura | Zendy; Masahiko Ishida | Zendy; Haruki Sugisawa | Zendy; Hiroto Ida | Zendy; Jafari Saeed | Zendy; Teruko TakanoYamamoto | Zendy

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Effect of interleukin-4 on orthodontic tooth movement and associated root resorption

Author(s) -

Zaki Hakami,

Hideki Kitaura,

Keisuke Kimura,

Masahiko Ishida,

Haruki Sugisawa,

Hiroto Ida,

Jafari Saeed,

Teruko TakanoYamamoto

Publication year - 2014

Publication title -

european journal of orthodontics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.252

H-Index - 84

eISSN - 1460-2210

pISSN - 0141-5387

DOI - 10.1093/ejo/cju016

Subject(s) - dental alveolus , chemistry , resorption , root resorption , periodontal fiber , saline , bone resorption , acid phosphatase , interleukin , dentistry , medicine , cytokine , biochemistry , enzyme

Interleukin-4 (IL-4) is a recognized immunomodulatory cytokine that regulates bone homeostasis. However, the influence of IL-4 on orthodontic tooth movement (OTM) and subsequent root resorption is still unknown. Therefore, the purpose of this study was to investigate the effect of IL-4 on tooth movement and its associated root resorption in a mouse model.

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