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AIM: To evaluate the effects of orthodontic treatment on systemic levels of the infl ammatory markers C-reactive protein(CRP), tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6).SUBJECTS AND METHOD: Seventeen subjects (11 girls and 6 boys, mean age 13.1 years) treated with fi xed appliancesand distalising headgear. Venous blood samples were taken from the cubital vein before treatment and then at three furthertime points during treatment of each subject two months apart. The sera from these blood samples were analysed usingenzyme-linked immunosorbent assay technology for CRP, TNF-α and IL-6 concentration levels.RESULTS: There was no signifi cant elevation of any of the three infl ammatory markers at any time point.CONCLUSIONS: This research provides evidence that conventional orthodontic treatment has no systemic immune responseand is therefore immunologically safe.link_to_subscribed_fulltex

ABSTRACTS OF LECTURES AND POSTERS * EUROPEAN ORTHODONTIC SOCIETY, 85th Congress Helsinki, Finland 2009, 10-14 June