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Mechanobiology of tooth movement
Author(s) -
S. Henneman,
Johannes W. Von den Hoff,
Jaap C. Maltha
Publication year - 2008
Publication title -
european journal of orthodontics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.252
H-Index - 84
eISSN - 1460-2210
pISSN - 0141-5387
DOI - 10.1093/ejo/cjn020
Subject(s) - mechanobiology , mechanotransduction , orthodontics , biology , neuroscience , microbiology and biotechnology , medicine
This review describes the mechanical and biological signalling pathways during orthodontic tooth movement and provides an update of the current literature. A theoretical model is introduced to elucidate the complex cascade of events after the application of an orthodontic force to a tooth. In this model, the events are divided into four stages: matrix strain and fluid flow, cell strain, cell activation and differentiation, and remodelling. Each stage is explained in detail and discussed using recent literature.

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