Effect of modest alcohol consumption over 1-2 weeks on the coronary microcirculation of normal subjects | Zendy

Sanjiv Kaul | Zendy; Todd Belcik | Zendy; Saul Kalvaitis | Zendy; Ananda R. Jayaweera | Zendy; Si Wan Choi | Zendy; Kevin Wei | Zendy

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Effect of modest alcohol consumption over 1-2 weeks on the coronary microcirculation of normal subjects

Author(s) -

Sanjiv Kaul,

Todd Belcik,

Saul Kalvaitis,

Ananda R. Jayaweera,

Si Wan Choi,

Kevin Wei

Publication year - 2010

Publication title -

european journal of echocardiography

Language(s) - English

Resource type - Journals

eISSN - 1525-2167

pISSN - 1532-2114

DOI - 10.1093/ejechocard/jeq042

Subject(s) - medicine , blood flow , microcirculation , cardiology , blood viscosity , coronary flow reserve , alcohol consumption , coronary circulation , alcohol , biochemistry , chemistry

It has been reported that imbibing red wine increases coronary blood flow reserve acutely. In the absence of changes in coronary driving pressure, any increases in coronary blood flow reserve should occur through a decrease in capillary resistance, which in turn is determined by capillary dimensions and whole-blood viscosity. Since alcohol intake is unlikely to acutely change capillary dimensions, we hypothesized that it must increase coronary blood flow reserve by reducing whole-blood viscosity.

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