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Semi-automated analysis of dynamic changes in myocardial contrast from real-time three-dimensional echocardiographic images as a basis for volumetric quantification of myocardial perfusion
Author(s) -
Federico Veronesi,
Enrico G. Caiani,
E. Toledo,
Cristiana Corsi,
Karen A. Collins,
Georgeanne Lammertin,
C. Lamberti,
RM Lang,
Victor MorAvi
Publication year - 2008
Publication title -
european journal of echocardiography
Language(s) - English
Resource type - Journals
eISSN - 1525-2167
pISSN - 1532-2114
DOI - 10.1093/ejechocard/jen209
Subject(s) - medicine , perfusion , contrast (vision) , translation (biology) , myocardial perfusion imaging , region of interest , nuclear medicine , radiology , artificial intelligence , biomedical engineering , computer science , biochemistry , chemistry , messenger rna , gene
Despite the potential of real-time three-dimensional (3D) echocardiography (RT3DE) to assess myocardial perfusion, there is no quantification method available for perfusion analysis from RT3DE images. Such method would require 3D regions of interest (ROI) to be defined and adjusted frame-by-frame to compensate for cardiac translation and deformation. Our aims were to develop and test a technique for automated identification of 3D myocardial ROI suitable for translation-free quantification of myocardial videointensity over time, MVI(t), from contrast-enhanced RT3DE images.

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